Eosinophilic
gastroenteritis is an uncommon
disease of unknown cause characterized by eosinophilic infiltration in various areas of the
gastrointestinal tract with gastrointestinal symptoms. It is generally classified according to the layer of the
gastrointestinal tract involved. Eosinophilic infiltration of the
serosa is the rarest form of presentation and may manifest eosinophilic
ascites. We
report a case of a 29-year-old
woman who experienced rapidly progressing abdominal distension and
pain. A diffuse erythematous change of the
gastric mucosa was observed on
gastroscopy. An abdominal computed
tomography and
colonoscopy showed diffuse wall thickening of the small bowel and
colon with a large amount of
ascites. Eosinophilic infiltration was confirmed by multiple
biopsies of the
gastrointestinal tract and
peritoneal fluid analysis. The
patient was treated with
corticosteroid and responded dramatically.