The records and electrodiagnostic studies (EDS) of 70 GBS patients were retrospectively evaluated, and divided into 2 groups according to the results of EDS. Group A (n=33) presented with F-waveabnormalities, and group B (n=26) exhibited normal findings. We compared laboratoryreports, clinical features, response to treatment, and prognosis between the 2 groups.
RESULTS:
Motor weakness was the most frequently observed symptom for either group. Clinically, the incidence of fever and upper respiratory symptoms differed between the 2 groups, while the prevalence of abnormal deep tendon reflex (DTR) was significantly higher in group A than B (P<0.05). Patients diagnosed with GBS had received intravenous immunoglobulintreatment 94% in group A and 58% in group B. Furthermore, significantly greater numbers of patients in group A showed H-reflexabnormalities and poor prognosis compared with group B (P<0.05).
CONCLUSION:
This study demonstrated that F-waves are a clinically important prognostic factor in GBS. F-waveabnormalities were associated with abnormal DTR and poor prognosis in patients. Limited studies have examined the link between F-waveabnormalities and clinical results; therefore, further randomized controlled studies are needed to confirm the clinical characteristics and efficacy of treatments.