PURPOSE: Maintenance of the normal hydration
state is one of the major purposes of
hemodialysis therapy in
patients with
end-stage renal disease .
Overhydration is an important and independent predictor of
mortality in
patients with
end-stage renal disease on regular
hemodialysis . BCM (
body composition monitor, FMC,
Germany ) reliably enables quantitative assessment of hydration status and
body composition . The aims of this study were to investigate the relationship between hydration status and clinical features and the
risk factors of
overhydration .
METHODS: We measured hydration status and
body composition of total 72
patients with
end-stage renal disease on regular
hemodialysis by BCM from June, 2009 to September, 2009. We also reviewed the clinical characteristics and
laboratory findings and comorbidities retrospectively.
RESULTS: The hydration status measured by BCM was correlated well with interdialytic
weight gain after 48 hours and 72 hours from last
hemodialysis treatment (r=0.42 p or =20%) and control
patients (relative hydration status <20%). In overhydrated
patients ,
serum iron level was lower than control
patients 48 hrs after last
hemodialysis (p<0.05).
CONCLUSION: This
cross-sectional study showed that hydration status measured by BCM was correlated well with interdialytic
weight gain although there was no significant clinical difference between overhydrated and control
patients with
end-stage renal disease on regular
hemodialysis .