Comparison of the Outcomes of Peroral Endoscopic Myotomy for Achalasia According to Manometric Subtype
Won-Hee KIM; Joo-Young CHO; Weon-Jin KO; Sung-Pyo HONG; Ki-Baik HAHM; Jun-Hyung CHO; Tae-Hee LEE; Su-Jin HONG.
Gut and Liver
; : 642-647, 2017.
Artículo
en Inglés
| WPRIM | ID: wpr-175166
BACKGROUND/
AIMS:
We evaluated whether manometric subtype is associated with treatment outcome in patients with achalasia treated by peroral endoscopic myotomy (POEM).METHODS:
High-resolution manometry data and Eckardt scores were collected from 83 cases at two tertiary referral centers where POEM is performed. Manometric tracings were classified according to the three Chicago subtypes.RESULTS:
Among the 83 cases, 48 type I, 24 type II, and 11 type III achalasia cases were identified. No difference was found in pre-POEM Eckardt score, basal lower esophageal sphincter (LES) pressure, or integrated relaxation pressure (IRP) among the type I, type II, and type III groups. All three patient groups showed a significant improvement in post-POEM Eckardt score (6.1±2.1 to 1.5±1.5, p=0.001; 6.8±2.2 to 1.2±0.9, p=0.001; 6.6±2.0 to 1.6±1.4, p=0.011), LES pressure (26.1±13.8 to 15.4±6.8, p=0.018; 32.3±19.0 to 19.2±10.4, p=0.003; 36.8±19.2 to 17.5±9.7, p=0.041), and 4s IRP (21.5±11.7 to 12.0±8.7, p=0.007; 24.5±14.8 to 12.0±7.6, p=0.002; 24.0±15.7 to 11.8±7.1, p=0.019) at a median follow-up of 16 months.CONCLUSIONS:
POEM resulted in a good clinical outcome for all manometric subtypes.
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WPRO
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