PURPOSE: Hemodialysis patients are at an increased
risk of
ischemic colitis because of accelerated arterial
vascular disease rate and
hypotension during
dialysis . But few data exist on the clinical features of
ischemic colitis in
patients with
chronic kidney disease including
dialysis patients in
Korea . The aim of this study is to identify the clinical features of
ischemic colitis in
patients with
chronic kidney disease (CKD).
METHODS: We retrospectively reviewed total 68
patients (63.9+/-16.2 years) with
ischemic colitis . We analyzed medical
history , colonoscopic findings, clinical characteristics, and compared them according to
kidney function.
RESULTS: Twenty-two (33.9%)
patients had CKD stage > or =3 at
diagnosis of
ischemic colitis .
Prevalence of
hypertension and diabetes was higher in
patients with CKD than those with normal
kidney function. High
leukocyte count and low
hemoglobin level were demonstrated at
diagnosis in CKD
patients . In addition, duration of
hospitalization in
patients with CKD was longer than
patients with normal
kidney function. However, there was no significant difference in right colonic involvement,
cardiovascular diseases , surgical intervention, and
mortality .
Hospitalization days was positively correlated with increased
leukocyte count (p=0.015) and decreased
albumin level (p=0.002), while that was negatively correlated with age-adjusted estimated
glomerular filtration rate (p=0.002).
CONCLUSION: Ischemic colitis in
patients with CKD had longer
hospitalization than in those with normal
kidney function. However, there was no significant difference in surgical intervention and
mortality .