Evaluation of the MicroScan MICroSTREP Plus Antimicrobial Panel for Testing beta-Hemolytic Streptococci and Viridans Group Streptococci / 대한진단검사의학회지
Sung-Ju KIM; Young UH; In-Ho JANG; Kwan-Soo LEE; Soon-Deok PARK; Kap-Jun YOON.
The Korean Journal of Laboratory Medicine
; : 185-190, 2011.
Artículo
en Inglés
| WPRIM | ID: wpr-193619
BACKGROUND:
In order to determine the clinical usefulness of the MicroScan (Siemens Healthcare Diagnostics, USA) MICroSTREP plus antimicrobial panel (MICroSTREP) for testing antimicrobial susceptibility of beta-hemolytic streptococci (BHS) and viridans group streptococci (VGS), we compared the accuracy of MICroSTREP with that of the CLSI reference method.METHODS:
Seventy-five BHS and 59 VGS isolates were tested for antimicrobial susceptibility to ampicillin, penicillin, cefotaxime, meropenem, erythromycin, clindamycin, levofloxacin, and vancomycin by using MICroSTREP and the CLSI agar dilution method.RESULTS:
The overall essential agreement with regard to minimum inhibitory concentrations (MICs) (within +/-1 double dilution) between MICroSTREP and the CLSI reference method was 98.2%, and categorical agreement (CA) was 96.9%. For the BHS isolates, the CA for erythromycin was 96.0%, whereas that for cefotaxime, meropenem, levofloxacin, and vancomycin (for ampicillin, penicillin, and clindamycin; 98.7%) was 100%. For the VGS isolates, the CA for penicillin was 84.7% and that for erythromycin, clindamycin, and vancomycin (for meropenem, 86.5%; for ampicillin, 88.1%; and for cefotaxime and levofloxacin, 96.6%) was 100%. All categorical errors of penicillin and ampicillin in the VGS isolates were minor.CONCLUSIONS:
The accuracy of MICroSTREP is comparable to that of the CLSI reference method, suggesting that this panel can be effective for testing antimicrobial susceptibility of BHS and VGS.
Biblioteca responsable:
WPRO
Texto completo
Documentos relacionados