The Effect of Diphenylhydantoin on the Action of Ouabain
Sung-Kyew KANG; Ok-Kyu PARK.
Korean Circulation Journal
; : 23-26, 1971.
Artículo
en Ko
| WPRIM | ID: wpr-197133
The effect of diphenylhydantoin on LD 50 of ouabain was investigated in frogs, using "one hour frog method". LD50 of ouabain in control group was 1.90 microg/10g. A dose of 100 microg/10g diphenylhydantion did not affect the systemic manifestations of the frogs, but increase the LD50 of ouabain to 2.60 microg/10g. The difference of LD50 of ouabain and potency ratio between control group and diphenylhydantoin-treated group was statistically significant.
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