The neuroradiologic findings of
neurosyphilis are variable. A 36-year-old man was admitted due to gradually progressing abnormal
behavior and
personality change. The
brain MRI revealed bilateral mesiotemporal hyperintensity on FLAIR and T2 weighted MR images.
Analysis of
serum and CSF demonstrated the presence of
antibodies to
Treponema pallidum. The
patient was treated with
penicillin, and he had clinical improvements.
Neurosyphilis can manifest with MR imaging
abnormalities similar to those of
herpes encephalitis.