Little knowledge is available on the characteristic differences between patients with atopic dermatitis (AD) with and without atopic march after childhood.
OBJECTIVE:
To observe and compare the phenotypes of patients with AD in regards to atopic march tendency at a single point.
In a total of 182 patients enrolled in the study, 93 patients with atopic march and 89 patients with non-atopic march were observed. When their serum-specific IgE levels or results of the skin prick test were compared between the two groups, there was no significant difference, except for a in the atopic march group. Analysis of AD severity, familyhistory of allergic diseases, and total IgE levels between the two groups showed no statistically significant differences.
CONCLUSION:
Our findings suggest that although no apparent phenotype characteristics could differentiate the presence of atopic march, the history of the patient's allergic diseases should be revalidated, and clinicians should watch out for future developments of atopic march when a patient shows a high-class sensitization rate to dustmite.