It is known that
rheumatoid arthritis (RA)
patients show increased
incidence of
multiple myeloma (MM), despite its rarity. Only one case of MM with seronegative RA was reported in
Korea, thus far. We
report a case of MM with seropositive RA. The
patient was a 66 year old
female who had been diagnosed with seropositive RA 4 years ago. Over the last 1 month, the
patient experienced general weakness and
weight loss of 10 kg. It was found that her
serum creatinine had increased and her
urine analysis showed
proteinuria. To evaluate
renal failure and
proteinuria, renal
biopsy,
bone marrow biopsy and
electrophoresis were carried out. A
diagnosis of myeloma cast nephropathy was made. We
report this rare case of MM represented as
acute renal failure during the
treatment for RA, and include a
review of the
literature.