<p><b>OBJECTIVE</b>To investigate
gender-related differences in
risk factors, clinical manifestation and outcomes in
patients with
aortic dissection (AD) from Guangzhou.</p><p><b>
METHODS</b>Consecutive
patients with AD admitted to our institute over the past 10 years were included in this retrospective
analysis.
Prevalence of
hypertension,
smoking, thickness of intraventricular septum and left ventricular posterior wall measured by
echocardiography, and outcomes were compared between
male and
female AD
patients.</p><p><b>RESULTS</b>There were more
male AD
patients than
female AD
patients (5.331) from the 418
patients.
Prevalence of
hypertension, thickness of intraventricular septum and left ventricular posterior wall were
similar in
male and
female AD
patients. Heavy
smoking history was 56.5% in
males and 13.6% in
females (P = 0.000). Acute
survival rate in
female patients tended to be better than that in
male patients.</p><p><b>CONCLUSIONS</b>There were significantly more
male AD
patients than
female AD
patients in this cohort.
Prevalence of heave
smoking in
male patients is 3 times higher than that in
female population.</p>