Progress in study of selective ERβ ligands / 药学学报
Jin-ya CAI; Jun-hao LI; Shi-hui DING; Juan ZHANG; Gui-xia LIU; Wei-hua LI; Yun TANG.
Acta Pharmaceutica Sinica
; (12): 658-667, 2015.
Artículo
en Zh
| WPRIM | ID: wpr-257086
Estrogen receptors (ERs) are members of nuclear receptors and related to several diseases such as cancer, inflammation and osteoporosis. ERs have two forms, ERα and ERβ, which have different functions and organism distributions. Compounds selectively targeting ERβ can regulate important physiological functions and avoid the side effects caused by targeting ERα. Therefore, selective ERβ ligands have received considerable research interest in recent years. In this article, different kinds of selective ERβ ligands were summarized and their structure-activity relationships were also analyzed.
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WPRO
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