<p><b>OBJECTIVE</b>To investigate the
diagnosis,
treatment and
prognosis of
adult prostatic
sarcoma.</p><p><b>
METHODS</b>The
records of 7
patients with
prostate sarcoma were reviewed in the
light of clinical manifestation,
laboratory examination,
therapeutic methods and histological subtypes. Several clinicopathological variables were assessed for prognostic significance.</p><p><b>RESULTS</b>Of the 7 cases, 3 were
leiomyosarcoma, 3
rhabdomyosarcoma and the other
malignant neurilemoma. Most
patients presented urinary obstruction, and the
diagnosis of
prostate sarcoma was established with ultrasound guided
biopsy. Histological subtypes were related to the rate of
survival. Two
patients received radical cystoprostatectomy and died 13 and 21 months respectively after operation. Two cases underwent total
pelvic exenteration, followed by
chemotherapy and/or
radiotherapy and still alive 15 months after operation. The other 3 received only
chemotherapy and/or
radiotherapy and died 7 months on average after
diagnosis.</p><p><b>CONCLUSION</b>The long-term
survival rate for
adults with
prostate sarcoma is low.
Early diagnosis and complete surgical resection offer
patients the best chance for
survival. Long-term
surveillance is necessary for the early
detection of
recurrence.</p>