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Analysis of saponins in Panax notoginseng by UPLC-LTQ-Orbitrap MS/MS / 药学学报

Wen XU; Xiao-Hui QIU; Jing ZHANG; Da-Yuan ZHU; Yi-Ming YANG; Chuan-Jian LU.
Acta Pharmaceutica Sinica ; (12): 773-778, 2012.
Artículo en Zh | WPRIM | ID: wpr-276245
A method for qualitative analysis of constituents in Panax notoginseng by UPLC-LTQ-Orbitrap mass spectrometry was established. Based on the high-resolution mass information, MS/MS fragmentation behaviors and chemical components from literatures, 43 compounds were identified or tentatively characterized. New type saponin aglycone, combined with malonyl-substituted and acetyl-substituted saponins were discovered and plausibly identified in this study. This work could be helpful for the quality control and further phytochemical studies of Panax notoginseng, and provided a good example for the analysis of chemical constituents in traditional Chinese medicine.
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