"Prescription embodied in Preparation", Chinesemedicine preparation, aims to study the specific form of Chinesemedicine from raw materials to preparation for acting on patients directly. Its development has gone through three stages according to the characteristics of raw materials pretreatment, including "direct smash and initial extraction for Chinesemateria medica", "Extensive extraction and preliminarily impurity for Chinesemateria medica" and "Refining and purification for Chinesemateria medica". With the development of new technologies and new theories, Chinesemedicine preparation emerged in a new stage structural components of Chinesemedicine, with the characteristics of definited material basis, clear mechanisms, determined ADME/T properties, reasonable drug release system designs and scientific productions quality controls. This requires multidisciplinary to solve systemly the problems of Chinesemedicine preparation. In this article, we reviewed the development of Chinesemedicine preparation in different times, and analyzed the development and the characteristics of Chinesemedicine preparation; and mainly focused on a fact that multidisciplinary promoted the study and development of Chinesemedicine preparation, especially in structural components of Chinesemedicine. It provides development direction and theoretical basis for Chinesemedicine preparation.