Churg-Strauss syndrome (CSS) or
allergic granulomatous angiitis is a rare
syndrome that is characterized by hypereosinophilic systemic necrotizing
vasculitis affecting small- to medium-sized
arteries and
veins. In general, it occurs in individuals with pre-existing allergic
asthma. When CSS appears in
patients, it has the following characteristics
eosinophilia of more than 10% in peripheral
blood, paranasal
sinusitis, pulmonary infiltrates, histological proof of
vasculitis with extravascular
eosinophils, and
mononeuritis multiplex or
polyneuropathy.
Therapeutic trials dedicated to
Churg-Strauss syndrome have been limited due to the rarity of this disorder and the difficulty in making a histological
diagnosis. Proper
treatment of
patients with CSS is not widely known. In this
case study, we
report on our experience with an unusual
patient case, characterized by
purpura and a perforation of the
small intestine after inadequate
steroid therapy.