Relationship between hepatitis B virus DNA and hepatitis B virus large envelope protein / 浙江大学学报·医学版
Huai-kai WEN; Jian YU; Xiao-yong LI; Hong-qun TAO; Xin-liang ZHANG.
Journal of Zhejiang University. Medical sciences
; (6): 386-389, 2010.
Artículo
en Zh
| WPRIM | ID: wpr-319890
<p><b>OBJECTIVE</b>To investigate the relationship between HBV DNA and hepatitis B virus large envelope protein (HBV-LP) in patients with chronic hepatitis B.</p><p><b>METHODS</b>Serum HBV DNA was detected by RT-PCR and the HBV-LP was detected by enzyme linked immunosorbent assay in 320 serum samples collected from patients with chronic hepatitis B.</p><p><b>RESULTS</b>There were no significant difference between positive rate of HBV-LP and that of HBV DNA in different HBeAg patterns (P>0.05). Serum HBV-LP levels were closely correlated with HBV DNA copies (r=0.949).</p><p><b>CONCLUSION</b>Serum HBV-LP is a reliable serological marker that can reflect the replication of HBV.</p>
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