Antithymocyte globulin (ATG) has long been used for immune-induction and anti-rejection
treatments for solid
organ transplantations. To date, few cases of ATG-induced
acute respiratory distress syndrome (ARDS) have been published. Here, we present a case of ARDS caused by a single low-
dose of ATG in a renal
transplant recipient and the subsequent
treatments administered. Although the
patient suffered from ARDS and
delayed graft function, he was successfully treated. We emphasize that the presence of such
complications should be considered when unexplained respiratory distress occurs. Early use of
corticosteroids,
adjustment of immunosuppressive regimens, and conservative fluid management, as well as empiric antimicrobial
therapies, may be effective
strategies for the
treatment of ARDS caused by ATG.