<p><b>OBJECTIVE</b>To evaluate the influence of simultaneous
pancreas-
kidney (SPK)
transplantation on the
quality of life of diabetic recipients with
end-stage renal disease.</p><p><b>
METHODS</b>We performed a retrospective
analysis of the data of diabetic
patients with
end-stage renal disease and evaluated the
quality of life of the recipients using SF-36
health survey.</p><p><b>RESULTS</b>One
patient died of
cerebrovascular accident, and 7
patients recovered smoothly. During the follow-up lasting for a mean of 23.3 months, the
blood glucose,
C-peptide and
creatine levels of the
patients remained stable. The score of 8 domains of SF-36 of the diabetic recipient at 2 years after SPK
transplantation showed a significant improvement compared with that before the operation,
similar to that of
Chinese normal
population(P > 0.05).</p><p><b>CONCLUSIONS</b>SPK
transplantation can achieve a significant improvement of the
quality of life of diabetic
patients with
end-stage renal disease.</p>