Leukocytospermia is a most common cause of
male infertility, but the distribution, origin and
role of
leukocytes in
semen are still controversial. Some
reports on leukocytospermia have indicated its negative effects on
semen parameters and even
in vitro fertilization (IVF). Recent
literature has made it clear that the most deleterious effect of leukocytospermia is that the increased
reactive oxygen species (ROS) may cause
sperm damage, leading to significantly increased
male infertility. The
treatment and prevention of leukocytospermia have been proven of help for improving
semen parameters.