<p><b>OBJECTIVE</b>To detect red fluorescence in the facial skin of healthy individuals and patients with seborrheic dermatitis (SD).</p><p><b>METHOD</b>Skinanalysis was performed to obtain the ultraviolet images of the facial skins of 61 healthy individuals and 64 SD patients, and the detection rate of red fluorescence was calculated.</p><p><b>RESULTS</b>The detection rate of the red fluorescence was 36.06% in healthy individuals and 70.31% in SD patients (χ(2)=14.728, P<0.005). Additionally, it was significantly higher in T zone, where sebumsecretion is high, than in U zone, where sebumsecretion is lower (χ(2)=11.529,P<0.05;χ(2)=23.757,P<0.05,respectively).</p><p><b>CONCLUSIONS</b>Red fluorescence exist in both healthy individuals and SD patients, and the detection rate is especially high in the latter. Meanwhile, red fluorescence may be related with sebumsecretion.</p>