Objective To know
prevalence of
metabolic syndrome (MS) and metabolic
abnormalities (MA) in
overweight and obese
children and
adolescents in Guangzhou,
China.
Methods Totally, 439
children and
adolescents aged six to 18 years were enrolled, including 129 obese, 115
overweight and 195 normal control ones. Their
body height,
body weight,
waist circumference,
hip circumference and
blood pressure were measured, as well as their
fasting blood glucose (FBG),
lipid profiles and
oral glucose tolerance test (OGTF). Results ①
Prevalence of MS in
overweight and obese
children and
adolescents was 20.9 % (27/129) and 10.4 % (12/115), respectively, 17.9 % (35/195) and 1.6% (4/244) in those with
insulin resistance and non-
insulin resistance, respectively.
Prevalence of MS, each component of MA and cluster of each components of MA all increased in linear trend with their
body mass index (BMI) or
insulin resistance increasing. ② BMI correlated with all metabolic
indicators and could independently predict
risk of MS. Conclusions
Prevalence of MS among
overweight and obese
children and
adolescents in Guangzhou was considerably high, and BMI can be used as a suitable index for their
obesity assessment in MS
diagnosis.