Objective To investigate the
prognosis and related factors of
community acquired
pneumonia (CAP).
Methods From August 2003 to March 2009, 689 CAP cases from 37
hospitals of 23 cities in
China were enrolled. The onset information and clinical outcomes in one month of onset were recorded. Pearson
Chi-square test and
Logistic regression test were performed using the SPSS 12.0
software to identify
prognosis-related factors. Results Among 689
patients there were 396
male and 293
female. The median age was (53 19) years old, 247
patients (35.8%) were≥65 years old. Forty four
patients died with a fatality rate of 6.4%. Univariate
analysis identified 19
risk factors, they were age≥65 years old,
smoking, aspiration, use of
antimicrobial agents in 3 months, use of immunodepressant in 2 months,
heart failure,
chronic renal failure, chronic
liver disease, eerebrovascular
disease, diabetes,
emaciation, altered mental status,
respiratory rate > 28/min,
pulse > 100/min, lower diastolic
blood pressure,
neutrophil ratio > 0.9, ALT >40 U/L, elevated
blood urea nitrogen level and PORT
classification ≥Ⅳ. By
multivariate analysis, use of
antimicrobial agents in 3 months,
respiratory rate > 28/min,
pulse > 100/min and PORT
classifications≥Ⅳ were identified as the independent
risk factors for
mortality. Conclusions The general fatality rate of CAP is low in
China. Use of
antimicrobial agents in 3 months,
respiratory rate > 28/min,
pulse > 100/min and PORT
classifications≥Ⅳ are independent
risk factors for
mortality.