BACKGROUND: With further
understanding of
deep venous thrombosis (DVT)following
total hip replacement ,reduction and prevention of DVT has become hot topic in clinical studies.The
reports of DVT formation factors remain controversial due to small samples,little statistical significance,
confusion of basic experimental and clinical results and lacks of
science .
OBJECTIVE: To explore the causes and factors for the early DVT following
total hip replacement and summarize
measures to prevent and treat early DVT to reduce
incidence of
complications .
METHODS: A total of 1780 cases of primary
total hip replacement operation were analyzed retrospectively.The statistical indexes included
sex ,age,body mass,other system
disease ,previous
hip joint operation,
anesthesia ,
operative time ,prosthetic fixation,
blood transfusion ,postoperative functional
exercise ,antithrombotics,and complication.Standardized database was built and analyzed by SPSS(version 13).
Regression analysis was performed using Binary
Logistic Regression .RESULTS AND
CONCLUSION: Of 1780 cases,136 had DVT.Age,other system
diseases ,
anesthesia ,prosthetic fixation,
blood transfusion ,postoperative functional
exercise and antithrombotics were correlated with early DVT(P < 0.05).Old age,
hypertension or diabetes,
general anesthesia ,fixation of
bone cement ,whole
blood transfusion were the
risk factors for early DVT following
total hip replacement ,while postoperative functional
exercise and antithrombotics were the
protective factors for DVT.The
incidence rate of early
complications can be reduced by the
methods such as dealing with perioperative
treatment carefully,effectively controlling the
chronic diseases ,efficient evaluation before
surgery ,precise manipulation,and the postoperative prophylactic
treatment and
nursing .