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Effect of mitiglinide calcium on fasting plasma fibroblast growth factor-21 level in patients with newly diagnosed type 2 diabetes mellitus / 中华内分泌代谢杂志
Yingying FAN
;
Gangyi YANG
;
Ling LI
;
Zhiyong LI
;
Yong LIAO
;
Chunrui CHENG
;
Shiguo TANG
;
Shengbing LI
;
Na LI
;
Yi WANG
.
Chinese Journal of Endocrinology and Metabolism
; (12): 143-145, 2012.
Artículo en Zh | WPRIM | ID: wpr-424548
Eighty-two newly-diagnosed type 2 diabetic
patients
with poor
glycemic control
were treated by mitiglinide
calcium
for 16 weeks.
Plasma
fibroblast growth factor
-21 ( FGF-21 ) level were evaluated.The relationship of
plasma
FGF-21 levels with
body mass index
,
body fat
,
waist-to-hip ratio
,
lipid
,
blood glucose
,HbA1c,and free fatty-
acid
were analyzed.
Plasma
FGF-21 was decreased significantly by
treatment
with mitiglinide
calcium
in type 2 diabetic
patients
,and it may
play
a
role
in the pathogenesis of
type 2 diabetes mellitus
.
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