The
osteocyte has been found to be an orchestrator of
bone remodeling.The damage of
bone leads to
osteocyte apoptosis.Sclerostin secreted by
osteocyte causes
feedback inhibition of
bone formation,so inhibition of sclerostin expression has become a new target of
treatment for
osteoporosis.It seems resonable to direct clinical practise and
treatment of
metabolic bone diseases through
understanding the function of
osteocyte in the process of
bone remodeling.