Current guidelines recommend the use of warfarin in the first 3 months after bioprosthetic valve replacement and suggest long-term anticoagulation only in patients with obvious risk factors for thrombosis. Despite at low risk of thromboembolism, we present a case of a 72-year-old malepatient with infected thrombus at bioprosthetic aortic valve with distal arterial embolization after 3 years of replacement surgery. The incidence of asymptomatic bioprosthetic valve thrombosis (BPVT) may be higher than anticipated and active surveillanceechocardiography is needed to early detect BPVT before leading to fatal complication.