Therapeutic effect of atorvastatin on aged patients with mild to moderate hypertension / 心血管康复医学杂志
Leng HAN; Bo LIU; Donglai CAO; Jun HE; Jie NI.
Chinese Journal of cardiovascular Rehabilitation Medicine
; (6): 309-311, 2014.
Artículo
en Zh
| WPRIM | ID: wpr-451987
Objective:
To explore therapeutic effect of atorvastatin on aged patients with mild to moderate hyperten-sion.Methods:
A total of 427 aged patients with mild to moderate hypertension treated in our hospital from Jul 2011 to Jul 2013 were randomly divided into routine treatment group (n=210)and atorvastatin group (n=217,received atorvastatin additionally based on routine treatment)according to number table.All patients were treated with a continuous 24 months.Therapeutic effect of controlling blood pressure,changes of blood pressure level and high sensitive C reactive protein (hsCRP)level and occurrence of adverse reactions during treatment were compared be-tween two groups.Results:
Compared with routine treatment group,there was significant rise in total effective rate of long-term (24 months)controlling blood pressure (76.8% vs.85.9%),and significant reductions in blood pres-sure [(145.3±10.1/88.6±6.7)mmHg vs.(136.9±6.8/83.0±5.2)mmHg]and hsCRP [(2.02±0.29)mg/L vs. (1.60±0.18)mg/L]level in atorvastatin group,P0.05).Conclusion:
Atorvastatin combined antihypertensive drugs can well control blood pressure and reduce inflammatory reactions,which is suitable for long term use in aged patients with hypertension.
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WPRO
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