Objective To investigate the
safety and
effectiveness of percutaneous balloon pulmonary valvuloplasty (PBPV) in the
treatment of
pulmonary stenosis (PS).
Methods The subjects were 52
patients with PS from 2007 to 2012, including 24
male and 28
female. Their age ranged from 1 year old to 56 year old and mean age was 9.2±7.6 years old. Their
body weight ranged from 10 kg to 60 kg and mean weight was 17.3±8.9 kg. All
patients were assessed with
electrocardiogram (
ECG),
chest X-ray, right
heart catheterization and right ventricular angiagraphy before the
procedure. Results All 52
patients received PBPV successfully. Comparing the transvalvular
pressure gradient before and after the operation, it decreased from 86.3±27.6 mmHg (1 mmHg=0.133 kPa) to13.8±7.7 mmHg, and statistically difference (P<0.01). Among these
patients, one
patient occurred
ventricular fibrillation and Aspen
syndrome (hypoxie-
ischemic encephalopathy), one
patient occurred respiratory and
cardiac arrest, 24
patients occurred
transient arrhythmia, one
patient had
hypotension, one
patient had
bradycardia and one
patient showed desaturation. All these symptoms resolved after appropriate
treatment during the PBPV. Two
patients had
hematoma in the
puncture point and 2
patients had reactive infundibular
stenosis after PBPV. Conclusions Performing the percutaneous balloon pulmonary valvoplasty on the
patients with
pulmonary stenosis is safe and effective. PBPV causes less
pain and can be used as the preferred
treatment for
pulmonary stenosis.