Objective:
To investigate the effect of
pancreaticojejunostomy on the occurrence of postoperative
pancreatic fistula (POPF) after
pancreaticoduodenectomy.
Methods:
Data from 145
patients with periampullary
tumor who underwent pancreaticoduode-nectomy in Tianjin Medical
University Cancer Institute and
Hospital between October 2008 and August 2013 were reviewed. Factors potentially associated with POPF were analyzed by Pearson
chi-square test and
Logistic regression analysis.
Results:
Among the 145
patients, 27 were diagnosed with POPF, including 5 grade A, 17 grade B and 5 grade C. Neither duct to
mucosa nor Blumgart pancreati-cojejunostomy was correlated with POPF in grade C. The univariate
analysis showed that
gender,
pancreatic cancer,
portal vein involve-ment, type of
pancreaticojejunostomy, texture of
pancreas, and diameter of the
main pancreatic duct were closely correlated with POPF. The
multivariate analysis using
Logistic regression showed that different pancreaticojejunal anastomoses and genders were independent predictors of POPF.
Conclusion:
Different types of pancreatic anastomoses are a
risk factor for POPF after
pancreaticoduodenectomy.