The aim of this study was to determine whether viral type
HPV-6 and
HPV-11 could have influence on the
clinical course of recurrent respiratory
papillomatosis in
children. The
detection of viral typing, using the
polymerase chain reaction (
PCR) was performed on
papilloma biopsies of 36
patients at ENT
Hospital HCM City from 3/2000 to 3/2004.
HPV-6 was detected in 17
patient's
biopsies and
HPV-11 in 19
biopsies. After the findings,
patients infected by
HPV-11 have more aggressive than
patients infected by
HPV-6 (73.7% vs 29.4%; p=0.008).
Patients with
HPV-11 have higher
prevalence of
tracheotomy and shorter interval
time between two operations than
patients with
HPV-6