Objective To observe and compare the bloodlipid level in patients with colorectal polyps.Methods One hundred and twenty patients with colorectal polyps adminated in Shuangshan Hospital of Anshan from January 2011 to January 2014 were selected as observations and 120 healthy check-ups were selected as control group.The levels of serum total cholesterol (TC), triglyceride (TG) and low density lipoprotein cholesterol(LDL-C) of two groups were detected.Based on the pathological type and position of colorectal polyps and patients' gender, the bloodlipid levels of sub-groups were compared.Results For observation group,there were single polyps in 81 cases ,multiple polyps in 39 cases and total colorectal polyps in 7 cases.There were 53 cases (44.17%) of hyperlipidemia (HLP).The levels of TC, TG and LDL-C of observation group were (5.26±0.97) mmol/L, (1.55±0.59) mmol/L, (2.88±0.67) mmol/L, significantly higher than those of control group ((4.51±1.02) mmol/L, (1.05±0.57) mmol/L, (2.43±0.39) mmol/L;t =4.08,4.27, 3.87, P<0.05).the incidence of HLP based on the different pathological types were not significantly changed (P > 0.05).The bloodlipid levels based on the different pathological types were not significantly changed(P>0.05).According to analysis results of adenomatous polyp, the incidence of tubular and villous adenoma HLP was significantly higher than that of tubular and villous adenoma(x2 =4.51, P<0.05), while there was no significant difference in term of the bloodlipid levels between the two groups(P>0.05).The specific bloodlipid levels were different (95% CI 1.695-5.276, 1.823-3.517, 1.634-4.186;P <0.05).Conclusion TC and TG increase in patients with colorectal polyps.The clinical diagnosis and treatment shall focus on the detection of bloodlipid levels.