Ten
dogs were enrolled in this study two healthy
dogs, two obese
dogs without other medical issues and six obese
dogs with underlying
diseases including
pemphigus,
chronic active hepatitis,
hyperadrenocorticism,
narcolepsy,
otitis media and heartworm
infection.
Pyrosequencing of the
16S rRNA gene to explore the gut bacterial diversity revealed that distal gut bacterial
communities of samples from
patients with
pemphigus,
otitis media and
narcolepsy consisted primarily of
Firmicutes, while the major phylum of the distal gut bacterial
communities in
patients with
chronic active hepatitis and
hyperadrenocorticism was
Fusobacteria.
Proteobacteria were the dominant phylum in heartworm infected obese
patients.