Hyperthyroid-associated EMA syndrome:four cases report and review of literature / 中华内分泌代谢杂志
Bin LU; Hongying YE; Zhaoyun ZHANG; Yehong YANG; Jie WEN; Xiaolong ZHAO; Xi WU; Yiming LI; Renming HU; Hong LIU.
Chinese Journal of Endocrinology and Metabolism
; (12): 790-792, 2015.
Artículo
en Zh
| WPRIM | ID: wpr-478849
[Summary] Four patients with hyperthyroid-associated exophthalmos, myxedema, acropachy ( EMA ) syndrome, including three male patients and one female patient were diagnosed with Graves′diseases and treated by 131 I therapy. Complaints of thyrotoxicosis were presented at the onset. Tibia myxedema and acropathy appeared, and eye symptoms aggravated in two patients after anti-thyroid drug therapy and 131 I therapy. Four cases were all given clobetasol propionate, miconazole nitrate, neomycin sulfate and urea cream alone or in combination with compound betamethasone local injection treatment, and three cases were given low-dose oral prednisone treatment. Complaints of tibia myxedema and eye symptoms were significantly improved after the treatment. Therefore, we should be wary of the occurrence of hyperthyroid-associated EMA syndrome after 131 I therapy. Corticosteroid might be the effective therapy for myxedema and eye symptoms of EMA syndrome.
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