Radiation-induced
cognitive impairment is hypothesized to occur because of dynamic interactions be -
tween multiple
cell types, including
astrocytes,
endothelial cells,
microglia,
neurons, and
oligodendrocytes.Cur-rent researche indicates that
radiation-induced changes include the decrease in
hippocampus neurogenesis , altera-tions of neuronal functions , particularly
synaptic plasticity , as well as the elevation of neuroinflammatory
cytokines .