Objective To investigate the value of guide-wire loop in interventional
therapy of
patients with
Budd-Chiari syndrome with
hepatic vein obstruction.
Methods A
retrospective study was conducted on 25
patients with
Budd-Chiari syndrome (BCS) with
hepatic vein obstruction treated from May 2011 to August 2014.The
technique of guide-wire loop was used in these
patients.The
pressure of the
hepatic vein was measured before and
after treatment.The difference in the
pressure was analyzed by the t test.Results All the
patients were treated successfully using guide-wire loop
angioplasty.No
complications of
bleeding,
pericardial tamponade and
liver capsule hemorrhage were observed.
After treatment,the
pressure of the
hepatic vein reduced from (48.3± 8.0) cmH2O to (20.9 ± 3.8) cmH2O (t =26.82,P < 0.05);The symptoms and physical signs of the
patients were relieved or disappeared.BCS-related symptoms reappeared on follow-up in 4
patients,2 were treated by balloon
dilation successfully.1
patient was treated with transjugular intrahepatic
portosystemic shunt (
TIPS) because of decompensated
liver cirrhosis.1
patient with
ankylosing spondylitis had
treatment failure and the symptoms relapsed for the third
time.Conclusion The
technique of guide-wire loop in interventional
therapy of
patients with
Budd-Chiari syndrome with
hepatic vein obstruction is safe and effective,and it can improve the overall success rate of
treatment.