Objective To investigate
hospital acquired
infections in
patients with
liver cirrhosis caused by relevant factors.
Methods From July 2008 to June 2013,the clinical data of 470 cases of
hospital acquired
infections patients with
chronic hepatitis B virus (HBV)
infection were retrospectively analyzed by
case-control study for the effective factors.Results
Hospital acquired rate was 29.1% (137/470).By
logistic regression analysis,the effective factors were
length of stay (OR =27.824,95% CI 7.187-98.386),invasive operation (OR =17.201,95% CI 4.245-71.303),a complication (OR =2.138,95% CI 1.030-4.377),preventive use of
antibiotics(OR =2.741,95%CI 1.816-4.010),
drinking history(OR=34.248,95%CI 13.045-82.328),
serum albumin(OR =17.258,95% CI 6.242-53.162),quantitative
PCR-HBVDNA (OR =4.859,95% CI 3.214 -7.625),
white blood cell (OR =4.271,95 % CI 1.520-12.157),c holinesterase (OR =2.761,95 % CI 1.523 -3.787) and anti
virus medicine(OR=0.128,95%CI 0.041-0.375) (P<0.05).Conclusion This study shows that
length of stay,invasive operation
history,
complications,low
white blood cell,low
serum protein,low
cholinesterase,the prophylactic use of
antibiotics,
hormone,high
PCR-HBVDNA quantitative and
drinking are the important
risk of
hospital acquired
infections infection factors of
patients of impact chronic HBV
infection.Applications of
antiviral drugs are effective in the prevention of chronic HBV
infection protection factors of
hospital acquired
infections infection patients.