Objective To study pulmonary wedge
angiography ( PWA ) with
hemodynamic the evaluation of
children with
congenital heart disease and
pulmonary artery hypertension ( PAH) .
Methods Hemodynamic measurement and pulmonary wedge
angiography were performed in 50
children with
congenital heart disease. Comparison and
analysis were made from the data obtained from PWA and
catheterization. Results After PWA, the
patients were categorized into 3 groups according to the measured
hemodynamics parametersgroup A [ n=15,
patients with normal mean
pulmonary artery pressure ( mPAP≤25 mmHg) and normal pulmonary vessel resistance (PVR﹤300 dyne?s?cm5)], group B [n=24,
patients with PAH (mPAP﹥25 mmHg) but normal PVR] and group C (n=11,
patients with PAH and elevated PVR (PVR≥300 dyne?s?cm5). Rote of tapering (ROT) was significant lower in group C than in group A and B (F=42. 559,P﹤0. 05).
Pulmonary circulation time (PCT) was higher in group C than in group A and B (F=6. 037,P﹤0. 05). ROT correlated negatively with PVR (r = -0. 606, P ﹤0. 05). PCT index correlated positively with PVR (r=0. 783,P=0. 01). There was no significant correlation between PCT and mean
pulmonary artery hypertension (mPAP). Conclusions PWA may help to make
quantitative analysis of the pulmonary vascular status in
patients with
congenital heart disease.