Total effective rate of ticagrelor group was significantly higher than that of clopidogrel group (93.4% vs .87.8% ,P=0.036);compared with clopidogrel group on 24h and 7d after operation ,there were signif‐icant reductions in platelet aggregation rate [24h(62.1 ± 5.2)% vs . (56.5 ± 5.4)% ,7d(47.3 ± 6.1)% vs . (38.7 ± 5.2)% ] and P2Y12 reaction unit [24h(218.1 ± 12.3) U vs . (201.3 ± 11.1) U ,7d(173.4 ± 11.8) U vs . (152.6 ± 12.6) U] in ticagrelor , P0. 05 all .