Objective To explore the effect of ultrasound assisted liposuction in vivo on clinical aesthetic plastic surgery. MethodsUltrasonic lipoplastics combined with swelling liposuction were used in 153 cases of the beauty seekers. Application of rountine tissue swelling technique with the transduction of ultrasound into fatty areas made atipose cells broken and emulsified, and it also easy to move the atipose tissue rich in connective fibres. Results All the patients were satified with the aesthetic effects after the operation. Smoothness and softness of the operated areas with obvious shrinkage of the skin were found with few complications. Conclusion Ultrasound assisted liposuction is an effective and simplified method and deserves to be widely used.