Objective: ①To detect the concentrations of
interleukin 1 ?(IL 1?) and
prostaglandin E 2 (
PGE 2) in periapical
exudates in the
patients with acute or chronic
periapical periodontitis ; ② To examine their correlations with clinical and radiographic findings of the involved
teeth .
Methods: The volume of periapical
exudates was quantified using the standard
paper point sampling
method ; the concentration of IL 1? and
PGE 2 was detected using
enzyme linked immunosorbent assay (
ELISA ) or
radioimmunoassay (RIA) in 40 cases with acute and in 40 with chronic periapical periodentitis.
Results: ①The volume(?l) of the
exudates in the cases with acute
periapical periodontitis and chronic were 27.10?15.70 and 3.12?2.88( P