Objective:
To study the clinical value and
telomerase activity of malignant
ascites treated by lifein combination with
cisplatin.
Methods:
48
patients with malignant
ascites were divided randomly into two groups.
Treatment group of 28 cases were treated with lifein and
cisplatin,
control group of 20 cases were treated with
cisplatin alone.
Telomerase activity was detected by semi-TRAP assay before
treatment,at the first week,the second week and the third week
after treatment,respectively.
Results:
the effective rates of
treatment group(89.3%) was much higher than that of
control group (60%),P