Objective To investigate the
association between the
phosphodiesterase 4D(PDE4D)
gene rs153031 polymorphism and the susceptibility of
unstable angina pectoris(UAP) in
Chinese Han
population of Changwu region .
Methods The PDE4D
gene rs153031 polymorphism was genotyped by Taqman probe in 172 UAP
patients(UAP group) ,as well as in
gender-and-age-matched 220 subjects without
coronary heart disease(CHD)(
control group) .Results In this crowd ,there was PDE4D
gene rs153031 poly-morphism in
patients with UAP and in subjects without CHD .Compared with
control group ,frequencies of GG ,GA ,AA
genotypes and G
allele of rs153031 in UAP group showed no statistical differences (P> 0 .05) .Conclusion In
Chinese Han
population of Changwu region ,PDE4D
gene rs153031 polymorphism shows no
association with the susceptibility of UAP .