Objective To analyze the clinical results and
risk factors according to cause-specific
survival and local
recurrence rates for the
patients with Ⅰ-Ⅱstage
breast cancer after
breast conservative therapy(BCT).
Methods During Jun.1988 to Jun.2005,304
patients with Ⅰ-Ⅱstage
breast cancer in the
General Hospital of PLA underwent
lumpectomy,axillary
lymph node dissection and definitive irradiation.All
patients received
adjuvant chemotherapy.The
patients with positive
estrogen hormone receptors received orally
tamoxifen administration.The median follow up was 8.1 years.Results For all the
patients,the total 5-year
survival rate,cause-specific
survival rate and local
recurrence-free
survival rate were 92.58%,93.46% and 86.26%,respectively.And the total 10-year overall
survival rate,cause-specific
survival rate and local
recurrence-free
survival rate were 85.29%,88.27% and 77.75%,respectively.The 5-year and 10-year local
recurrence rates were 5.5% and 11.7%,respectively.The univariate and mutivariate analyses revealed that the age(4)were the
risk factors according to cause-specific
survival rates.The age(