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Therapeutical effects of salvianolic acid B on myocardial infarction in dogs / 中成药

Lin LI; Lisha SUN; Jiangping XU.
Artículo en Zh | WPRIM | ID: wpr-571960

AIM:

To study the therapeutical effects of salvianolic acid B (Sal B) on myocardial infarction(MI) in dogs.

METHODS:

The models of myocardial infarction were produced by ligation of the left anterior descending (LAD) coronary artery in the anaesthetized dogs. The extent of myocardial ischemia was detected by epicardial-electrocardiogram and the extent of infarction was determhled by N-BT staining method. The parameter of lactate dehydrogenase was determined in the serums of dogs.

RESULTS:

It was indicated that the adminstration of Sal B(1、3 and 10mg/kg) by the way of intravenous injection reduced the extent of myocardial infarction (N-ST) ( P
Biblioteca responsable: WPRO