In vitro experimental study of apoptosis of BEL-7402 cells induced by selenium exo-polysaccharide of Porphyridium sp. (Se-PSP) / 中国海洋药物
Jinghua ZHU; Wei ZHANG; Min WANG; Chaojun LI; Chengwu ZHANG.
Chinese Journal of Marine Drugs
; (6)2000.
Artículo
en Zh
| WPRIM | ID: wpr-590539
Objective To observe the effects of selenium extracellular polysaccharide of Porphyridium sp(Se-PSP) on the growth and apoptosis of BEL-7402 tumor cell line.Methods The Se-PSP was obtained from a sort of culture medium with some selenous acid solution.In vitro,human tumor cells were cultured in sorts of PSP or Se-PSP liquors with different concentrations,and the result of which was determined by MTT,Focus apoptosis assay and DNA fragmentation.Results and Conclusion Se-PSP(80mg?L-1) displayed strong growth inhibitory effects against BEL-7402 human cancer cell line,and induced the apoptosis of BEL-7402 cells.
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