Objective To evaluate the
prognosis value of
heart‐type fatty‐
acid binding protein(H‐FABP)and
myeloperoxidase (MPO) in non‐ST elevation
acute coronary syndromes(NSTE ACS) .
Methods 181 NSTE ACS
patients were divided into 4 groups according to the level of H‐FABP and MPO ,and the baselines of 4 groups such as
gender ,age ,
hypertension ,
smoking ,body mass in‐dex ,
diabetes mellitus ,
hyperlipidemia were compared .The
incidences of
adverse cardiac events in 4 groups were compared after a 2 years′follow‐up .Results By multivariate COX regression
adjustment for other
risk factors ,the
relative risk(RR) of H‐FABP for
adverse cardiac events was 2 .023(95% CI1 .029 -3 .987 ,P=0 .002) ,and MPO was (95% CI2 .196 -5 .325 ,P< 0 .05) .The 2 years′follow‐up showed the
incidence of
adverse cardiac events in NSTE ACS
patients with higher H‐FABP and MPO levels was higher than the NSTE ACS
patients with one or two
indicators of normal levels .Conclusion The combined application of H‐FABP and MPO could has
clinical significance for the
prognosis of
patients with NSTE ACS .