Objective To analyze the clinical characteristics of chronic
intestinal pseudoobstruction (
CIPO).
Methods Clinical data of 43
patients with
CIPO admitted in
Peking Union Medical College
Hospital from January 2012 to December 2016 were retrospectively reviewed.The clinical manifestations,
laboratory examinations,images,
treatment and
prognosis of
CIPO patients were analyzed.Results There were 14
males and 29
females with an mean age of (41.9 ± 16.1) years.Among 43
patients,32 were admitted in
Gastroenterology Department,6 in General
Medicine Department and 5 in
Rheumatology Department.Twenty two cases were primary
CIPO and 21 cases were
secondary.The main clinical manifestations were abdominal distension (93.0%),
abdominal pain (67.4%),
vomiting (67.4%),
diarrhea (46.5%) and
constipation (41.9%).All 43
patients had decreased
body weight and
body mass index (BMI);23.3% (10/43)
patients were complicated with
anxiety and
depression.53.5% (23/43)
patients presented
anemia and 55.8% (24/43)
patients presented
hypoalbuminemia.All
patients with
CIPO underwent abdominal
X-ray,which showed
intestinal obstruction;but there was no evidence of mechanical obstruction.The average length of
hospital stay was (28.4 ± 13.9) d.Twenty three cases underwent gastric
decompression;28 cases (65.1%) received
parenteral nutrition,and 21 cases (48.8%) received
enteral nutrition;and 9 abdominal operations were performed in 8
patients.Conclusion When clinical symptoms of
intestinal obstruction appear without mechanical cause,
CIPO should be considered and
secondary factors should be screened.
Unnecessary surgery should be avoided in
CIPO patients.