Objective:
To investigate the relationship between FA,ET-1,Hcy and
VEGF in
patients with
pregnancy induced hypertension.
Methods:
Selected 80 cases of
patients with
pregnancy induced hypertension who were treated in our
hospital from January 2013 to September 2016,divided into A group (40 cases),and
preeclampsia and
preeclampsia B group (40 cases),60 cases of normal late
pregnant women as C group,60 cases of normal non
pregnant women as D group.The
plasma levels of FA,ET-1,Hcy and
VEGF in each group were detected,and the correlation
analysis was performed.
Results:
The
plasma levels of FA and
VEGF of group B were lowest in the four groups (P<0.05),the
plasma ET-1 and Hcy levels of group B were highest (P<0.05).The
plasma FA and
VEGF levels of
women with
pregnancy induce
hypertension were lower than those of the healthy late
pregnant women.The
plasma ET-1 and Hcy levels were higher (P<0.05).The multivariate
logistic regression analysis showed that FA,ET-1,Hcy and
VEGF levels were
risk factors for
pregnancy induce
hypertension.
Conclusion:
The elevation of
plasma Hcy level caused by FA
deficiency in
pregnancy might be related to the development of the
disease and the
incidence of
pregnancy induced hypertension syndrome,
VEGF might be an important factor in the occurrence and development of
pregnancy induced hypertension syndrome.