Objective To evaluate the
efficacy of 125Ⅰ
brachytherapy alone for the
treatment of recurrent
parotid gland carcinoma.
Methods Recurrent
parotid gland carcinoma patients (n =24) treated by 125Ⅰ
brachytherapy alone between 2006 and 2013 at
Peking University Hospital of
Stomatology were enrolled in this
retrospective study.All
patients underwent
surgery or
radiotherapy.The local control rate,
survival rate,and side effects were evaluated.Results The median follow-up
time was 21 months (range,4-59 months).Among the 24
patients,6 had local failure and 10 died during the follow-up period.The 1-and 3-year overall
survival rates,
progression-free survival rates,local control rates were 74.8% and 39.3%,74.8% and 31.5%,82.0% and 69.4%,respectively.No grade 3 or over
radiation injury was found.Conclusions 125Ⅰ
seed brachytherapy alone could provide an ahernative
treatment method for inoperable recurrent
parotid gland carcinoma patients.